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Abilify is an atypical antipsychotic medication used to treat multiple mood disorders. It is often prescribed in conjunction with other medications to treat major depressive disorder. Abilify is an atypical antipsychotic medication. This newer class of antipsychotic medications does not produce the same extrapyramidal symptoms having to do with coordination and movement or tardive dyskinesia involuntary movements of the lips, tongue, face, trunk or extremities but are still able to control psychosis.